Description: Ubiquitin Family Modifiers and the Proteasome Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Reviews and Protocols Author(s): R. Jurgen Dohmen, Martin Scheffner Format: Paperback Publisher: Humana Press Inc., United States Imprint: Humana Press Inc. ISBN-13: 9781493959051, 978-1493959051 Synopsis The ubiquitin-proteasome system (UPS) and ubiquitin-related modifiers are not only involved in cellular protein quality control but also in the regulation of many fundamental cellular processes/pathways as well as in their disease-relevant aberrations. Ubiquitin Family Modifiers and Proteasome: Reviews and Protocols presents both novel developments in UPS research and important methods related to the main recent advances in the field of ubiquitin family modifiers. Divided into five convenient sections, this volume focuses on the enzymology and substrate identification of ubiquitin family modifiers, the recognition and chain formation of these modifiers, the analysis of proteasome biogenesis and function, protein quality control, and finally the use of small molecules and strategies to study or manipulate the function of the UPS and of ubiquitin family modifiers, respectively. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Ubiquitin Family Modifiers and Proteasome: Reviews and Protocols will be of great use to investigators and students engaged in both basic and applied research in life sciences.
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Book Title: Ubiquitin Family Modifiers and the Proteasome
Number of Pages: 666 Pages
Language: English
Publication Name: Ubiquitin Family Modifiers and the Proteasome: Reviews and Protocols
Publisher: Humana Press Inc.
Publication Year: 2016
Subject: Chemistry
Item Height: 254 mm
Item Weight: 1732 g
Type: Textbook
Author: Martin Scheffner, R. Jurgen Dohmen
Series: Methods in Molecular Biology
Item Width: 178 mm
Format: Paperback